The state previously had a 15-week ban, but the six-week ban took effect in May. Florida’s ban has effectively shut off abortion access in the South, where neighboring states already enforce near-total abortion bans or severe restrictions. Abortion rights advocates were hoping to change that, and spent nearly $100 million on the effort.

DeSantis and opponents to Amendment 4 argued the ballot measure's authors are "lying" to Floridians, and words used, like "health care provider" and "viability" leave too much room for "outsiders" and unqualified practitioners to come to Florida and perform unsafe procedures.