denali news - Search News

Denali, ALS

ALS drugs from Denali, Calico come up short, marking setback for Healey trial

Denali’s medicine and a similar one from Calico Life Sciences and AbbVie were not much different than a placebo, bringing the tally of failed drugs in the innovative “Healey platform trial” to seven.

BioSpace · 20h

HEALEY ALS Trial Serves Up More Disappointment as Denali, AbbVie/Calico Fail

Misses from amyotrophic lateral sclerosis hopefuls Denali Therapeutics and partners AbbVie and Calico Life Sciences mark the latest setbacks for the controversial platform trial, the results from which have largely mirrored the dismal success rate in ALS overall.

Reuters · 4d

Denali Therapeutics' ALS drug fails in mid-to-late stage trial

Denali Therapeutics said on Monday its experimental drug failed to meet the main goal of a mid-to-late stage trial involving patients with amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease.

Business Insider · 4d

Denali Therapeutics announces HEALEY ALS trial regimen misses endpoints

Denali Therapeutics (DNLI) announced topline results from an analysis of Regimen G of the Phase 2/3 HEALEY ALS Platform Trial evaluating eIF2B

BioSpace · 4d

Denali Suffers Another ALS Fail With Phase II/III Flop

Denali’s failure on Monday continues biopharma’s losing streak against amyotrophic lateral sclerosis. PTC Therapeutics and Amylyx have seen similarly disappointing results.

GMC Celebrates 25 Years Of The Denali

To commemorate the 25th anniversary of Denali, GMC is offering customers a special 25th Anniversary Denali Package available ...

Motorious on MSN18h

2024 Ford Mustang GT Battles Porsche 911, Tesla Model Y, and GMC Denali on the Dragstrip

Ford Mustang GT takes on a Porsche 911, Tesla Model Y, and GMC Denali in a series of quarter-mile drag races. The 2024 Ford ...

Denali Reverses Its Fortunes With 'Too Early' Miss In ALS Treatment

Denali Therapeutics shares reversed higher on Tuesday after the drugmaker's ALS treatment failed in a six-month study.

STAT2d

Denali Therapeutics spinout raises $200M as neuro company resets

Tenvie Therapeutics is making hay from an R&D shift at Denali Therapeutics, acquiring several of its neuroscience drug ...

Why biotech startup Tenvie sees promise in drugs from founders' old company

About a year ago, Tenvie President and Chief Scientific Officer Tony Estrada approached Denali CEO Ryan Watts and others in ...

Investor's Business Daily on MSN3d

Denali Therapeutics Ratchets Up Losses On Misstep In ALS Treatment. Why The Game Isn't Over Yet.

Denali Therapeutics shares slumped for the second straight day Tuesday after the drugmaker's ALS treatment failed in a ...

Denali: Despite ALS Primary Endpoint Failure, Possible Path Forward Remains

Denali Therapeutics Inc.'s stock remains stable despite trial setback in ALS. BLA filing for MPS II treatment on track. Click ...

1don MSN

Pressure on China and pure 'trolling': Why Trump is pushing an expansionist agenda

The president-elect is suddenly pushing to annex Greenland, reclaim the Panama Canal and absorb Canada, provoking longtime ...

Denali Therapeutics Announces U.S. FDA Breakthrough Therapy Designation Granted to Tividenofusp Alfa for the Treatment of Hunter Syndrome (MPS II)

Denali Therapeutics Inc. (NASDAQ: DNLI), today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation for tividenofusp alfa (DNL310) for the treatment ...

Hosted on MSN2d

Denali Fault Mystery Unveiled: A Geological Breakthrough Reshapes North America’s History

A 620-mile geological enigma that has baffled scientists for decades has finally been solved. The Denali Fault, a massive ...

Results that may be inaccessible to you are currently showing.

Hide inaccessible results

Denali, ALS

Related topics